Vagus nerve stimulation and refractory depression
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چکیده
منابع مشابه
Vagus nerve stimulation for refractory epilepsy
Vagus nerve stimulation (VNS) is a neurophysiological treatment for patients with medically or surgically refractory epilepsy. Since the first human implant in 1989, more than 10 000 patients have been treated with VNS. Two randomized controlled studies have shown a statistically significant decrease in seizure frequency during a 12-week treatment period versus a baseline period when 'high stim...
متن کاملVagus Nerve Stimulation for Refractory Epilepsy
Context: Vagus nerve stimulation (VNS) is a relatively new treatment for epilepsy. Past studies have proposed that the antiepileptic action is related to the effect on the brainstem reticular activating system, and is mediated largely by the widespread release of two inhibitory agents (gamma aminobutyric acid [GABA] and glycine). Objective: To confirm the safety and efficacy of vagus nerve stim...
متن کاملVagus Nerve Stimulation in Refractory Epilepsy: State of the Art
Even if the notion of refractory epilepsy is difficult to define precisely, it is widely admitted that it corresponds to the failure of two or more drugs and occurrence of one or more seizures per month over 18 months. Approximately 30 to 35% of epileptic patients will experience refractory epileptic periods in their lifetime despite maximal antiepileptic medications or they will suffer from se...
متن کاملVagus nerve stimulation for refractory idiopathic generalised epilepsy
We reviewed our experience with vagus nerve stimulation (VNS) in 165 patients with medically refractory epilepsy (138 partial epilepsy (PE), 13 symptomatic generalised epilepsy (SGE), 14 idiopathic generalised epilepsy (IGE)). Average duration of VNS therapy was 21.6 months. A 50% or greater reduction in seizure frequency was achieved in 47.1% of the PE group, 46.1% of the SGE group, and 57.1% ...
متن کاملVagus nerve stimulation in refractory epilepsy: SPECT activation study.
UNLABELLED Left-sided vagus nerve stimulation (VNS) is an efficacious treatment for patients with refractory epilepsy. The exact mechanism of action remains to be elucidated. This study investigated the acute effects of initial VNS in patients with refractory complex partial epilepsy with or without secondary generalization (complex partial seizures [CPS] +/- SG) by means of a perfusion activat...
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ژورنال
عنوان ژورنال: British Journal of Psychiatry
سال: 2003
ISSN: 0007-1250,1472-1465
DOI: 10.1192/bjp.183.3.181